Role Of Micror-122 In Hepatocarcinogenesis Using Conditional Knockout Mice

Project: Research project

Project Details

Description

Project aims:
1. Validate functional targets of miR-122 that are identified in the wild type liver transcriptome by unbiased HITS-CLIP and RNA-seq approach using miR-122KO livers as a negative control.
2. Investigate anti-correlation between miR-122 and these targets in primary human HCC. We will focus on the targets that promote tumorigenesis at different stages.
StatusFinished
Effective start/end date1/2/1629/2/20

Funding

  • Molecular Pathogenesis Unit, NINDS, National Institutes of Health: €75,000.00

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