14 MeV neutrons for medical application: A scientific case for

M. Capogni, A. Pietropaolo, L. Quintieri, A. Fazio, M. Pillon, P. De Felice, A. Pizzuto

Research output: Contribution to conferencePaper

Abstract

99Tcmis a widely used radionuclide for SPECT (Single Photon Emission Computed Tomography) diagnostics thanks to its short half-life (about 6h) and the low-energy gamma ray emission (140 keV) well suited for diagnostic devices. The specific method for producing99Tcmvia100Mo(n,2n)99Mo reaction, as it was investigated in ENEA, is discussed in detail in this paper. The99Mo activity achieved by means of 14 MeV neutron irradiation on natural Molybdenum sample irradiated at the Frascati Neutron Generator (FNG) facility, at the Research Centre of ENEA-Frascati, was accurately assessed, by tracing it to the activity standards provided by the Italian National Institute of Ionizing Radiation Metrology (INMRI), located at the Research Centre of ENEA-Casaccia. The whole experiment carried out in ENEA was supported by simulations performed with the Fluka Monte Carlo code, whose predictions have been benchmarked against the experimental data collected at ENEA-FNG, relying on the traceability to the activity standards developed and maintained at the ENEA-INMRI Radioactivity laboratories.
Original languageEnglish
DOIs
Publication statusPublished - 4 Jun 2018
Externally publishedYes
Event22nd Meeting of the International Collaboration on Advanced Neutron Sources, ICANS 2017 - Oxford, United Kingdom
Duration: 4 Jun 2018 → …

Conference

Conference22nd Meeting of the International Collaboration on Advanced Neutron Sources, ICANS 2017
CountryUnited Kingdom
CityOxford
Period4/6/18 → …

Fingerprint

neutrons
generators
neutron irradiation
tracing
radioactivity
half life
ionizing radiation
radioactive isotopes
metrology
molybdenum
tomography
gamma rays
photons
predictions
simulation
energy

All Science Journal Classification (ASJC) codes

  • Physics and Astronomy(all)

Cite this

Capogni, M., Pietropaolo, A., Quintieri, L., Fazio, A., Pillon, M., De Felice, P., & Pizzuto, A. (2018). 14 MeV neutrons for medical application: A scientific case for. Paper presented at 22nd Meeting of the International Collaboration on Advanced Neutron Sources, ICANS 2017, Oxford, United Kingdom. https://doi.org/10.1088/1742-6596/1021/1/012038
Capogni, M. ; Pietropaolo, A. ; Quintieri, L. ; Fazio, A. ; Pillon, M. ; De Felice, P. ; Pizzuto, A. / 14 MeV neutrons for medical application: A scientific case for. Paper presented at 22nd Meeting of the International Collaboration on Advanced Neutron Sources, ICANS 2017, Oxford, United Kingdom.
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Capogni, M, Pietropaolo, A, Quintieri, L, Fazio, A, Pillon, M, De Felice, P & Pizzuto, A 2018, '14 MeV neutrons for medical application: A scientific case for', Paper presented at 22nd Meeting of the International Collaboration on Advanced Neutron Sources, ICANS 2017, Oxford, United Kingdom, 4/6/18. https://doi.org/10.1088/1742-6596/1021/1/012038

14 MeV neutrons for medical application: A scientific case for. / Capogni, M.; Pietropaolo, A.; Quintieri, L.; Fazio, A.; Pillon, M.; De Felice, P.; Pizzuto, A.

2018. Paper presented at 22nd Meeting of the International Collaboration on Advanced Neutron Sources, ICANS 2017, Oxford, United Kingdom.

Research output: Contribution to conferencePaper

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T1 - 14 MeV neutrons for medical application: A scientific case for

AU - Capogni, M.

AU - Pietropaolo, A.

AU - Quintieri, L.

AU - Fazio, A.

AU - Pillon, M.

AU - De Felice, P.

AU - Pizzuto, A.

PY - 2018/6/4

Y1 - 2018/6/4

N2 - 99Tcmis a widely used radionuclide for SPECT (Single Photon Emission Computed Tomography) diagnostics thanks to its short half-life (about 6h) and the low-energy gamma ray emission (140 keV) well suited for diagnostic devices. The specific method for producing99Tcmvia100Mo(n,2n)99Mo reaction, as it was investigated in ENEA, is discussed in detail in this paper. The99Mo activity achieved by means of 14 MeV neutron irradiation on natural Molybdenum sample irradiated at the Frascati Neutron Generator (FNG) facility, at the Research Centre of ENEA-Frascati, was accurately assessed, by tracing it to the activity standards provided by the Italian National Institute of Ionizing Radiation Metrology (INMRI), located at the Research Centre of ENEA-Casaccia. The whole experiment carried out in ENEA was supported by simulations performed with the Fluka Monte Carlo code, whose predictions have been benchmarked against the experimental data collected at ENEA-FNG, relying on the traceability to the activity standards developed and maintained at the ENEA-INMRI Radioactivity laboratories.

AB - 99Tcmis a widely used radionuclide for SPECT (Single Photon Emission Computed Tomography) diagnostics thanks to its short half-life (about 6h) and the low-energy gamma ray emission (140 keV) well suited for diagnostic devices. The specific method for producing99Tcmvia100Mo(n,2n)99Mo reaction, as it was investigated in ENEA, is discussed in detail in this paper. The99Mo activity achieved by means of 14 MeV neutron irradiation on natural Molybdenum sample irradiated at the Frascati Neutron Generator (FNG) facility, at the Research Centre of ENEA-Frascati, was accurately assessed, by tracing it to the activity standards provided by the Italian National Institute of Ionizing Radiation Metrology (INMRI), located at the Research Centre of ENEA-Casaccia. The whole experiment carried out in ENEA was supported by simulations performed with the Fluka Monte Carlo code, whose predictions have been benchmarked against the experimental data collected at ENEA-FNG, relying on the traceability to the activity standards developed and maintained at the ENEA-INMRI Radioactivity laboratories.

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Capogni M, Pietropaolo A, Quintieri L, Fazio A, Pillon M, De Felice P et al. 14 MeV neutrons for medical application: A scientific case for. 2018. Paper presented at 22nd Meeting of the International Collaboration on Advanced Neutron Sources, ICANS 2017, Oxford, United Kingdom. https://doi.org/10.1088/1742-6596/1021/1/012038