A microdosimetry study for a realistic shaped nucleus

A. Denzi, J.A.A. Escobar, C. Nasta, C. Merla, B. Benassi, C. Consales, F. Apollonio, M. Liberti

Research output: Contribution to conferencePaper

1 Citation (Scopus)

Abstract

In the last decades, the effects of ultrashort pulsed electric fields have been investigated demonstrating their capability to be involved in a great number of medical applications (e.g. cancer, gene electrotransfer, drug delivery, electrofusion). In particular, experiments in literature demonstrate that internal structures can be involved when pulse duration is reduced. Up to now, the mechanism that permits the electroporation phenomenon has not been completely understood and hence atomistic, microdosimetry and dosimetry models have been developed to help in this field. Aim of this work is to demonstrate the importance of realistically model also the internal organelles to obtain predictive results of effects at sub-cellular level with a microdosimetry model.
Original languageEnglish
DOIs
Publication statusPublished - 13 Oct 2016
Externally publishedYes
Event38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2016 - Orlando, United States
Duration: 13 Oct 2016 → …

Conference

Conference38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2016
CountryUnited States
CityOrlando
Period13/10/16 → …

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All Science Journal Classification (ASJC) codes

  • Signal Processing
  • Biomedical Engineering
  • Computer Vision and Pattern Recognition
  • Health Informatics

Cite this

Denzi, A., Escobar, J. A. A., Nasta, C., Merla, C., Benassi, B., Consales, C., ... Liberti, M. (2016). A microdosimetry study for a realistic shaped nucleus. Paper presented at 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2016, Orlando, United States. https://doi.org/10.1109/EMBC.2016.7591650