A piezoelectric quartz crystal sensor applied for thrombin-binding aptamers

Ilaria Lamberti, Jan Rakitka, Tibor Hianik, Lucia Mosiello

Research output: Contribution to conferencePaper

1 Citation (Scopus)

Abstract

The temperature-dependent UV spectroscopy and thickness shear mode acoustic method were applied to study of thermodynamics and binding properties of DNA aptamers sensitive to thrombin depending on the substitution of bases in G-quadruplex. The substitution of thymidines by adenines in TT and TGT loops of G-quadruplex resulted in destabilization of aptamers and in decrease of sensitivity to human thrombin. © 2011 Springer Science+Business Media B.V.
Original languageEnglish
DOIs
Publication statusPublished - 2011
Externally publishedYes
Event15th Italian Conference on Sensors and Microsystems, AISEM 2010 - , Italy
Duration: 1 Jan 2011 → …

Conference

Conference15th Italian Conference on Sensors and Microsystems, AISEM 2010
CountryItaly
Period1/1/11 → …

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All Science Journal Classification (ASJC) codes

  • Industrial and Manufacturing Engineering

Cite this

Lamberti, I., Rakitka, J., Hianik, T., & Mosiello, L. (2011). A piezoelectric quartz crystal sensor applied for thrombin-binding aptamers. Paper presented at 15th Italian Conference on Sensors and Microsystems, AISEM 2010, Italy. https://doi.org/10.1007/978-94-007-1324-6_73