Intraoperative radiation therapy is a special radiotherapy technique, which enables a high dose of radiation to be given in a single fraction during oncological surgery. The major stumbling block to the large-scale application of the technique is the transfer of the patient, with an open wound, from the operating room to the radiation therapy bunker, with the consequent organisational problems and the increased risk of infection. To overcome these limitations, in the last few years a new kind of linear accelerator, the Novac 7, conceived for direct use in the surgical room, has become available. Novac 7 can deliver electron beams of different energies (3, 5, 7 and 9 MeV), with a high dose rate (up to 20 Gy/min). The aim of this work, funded by ENEA in the framework of a research contract, is the development of an innovative system for on-line measurements of 2D dose distributions and electron beam characterisation, before radiotherapy treatment with Novac 7. The system is made up of the following components: (a) an electron-light converter; (b) a 14 bit cooled CCD camera; (c) a personal computer with an ad hoc written software for image acquisition and processing. The performances of the prototype have been characterised experimentally with different electron-light converters. Several tests have concerned the assessment of the detector response as a function of impulse number and electron beam energy. Finally, the experimental results concerning beam profiles have been compared with data acquired with other dosimetric techniques. The achieved results make it possible to say that the developed system is suitable for fast quality assurance measurements and verification of 2D dose distributions. © 2003 Elsevier B.V. All rights reserved.
|Pages (from-to)||616 - 620|
|Number of pages||5|
|Journal||Nuclear Instruments and Methods in Physics Research, Section B: Beam Interactions with Materials and Atoms|
|Publication status||Published - Jan 2004|
All Science Journal Classification (ASJC) codes
- Nuclear and High Energy Physics
Casali, F., Rossi, M., Morigi, M. P., Brancaccio, R., Paltrinieri, E., Bettuzzi, M., ... Vignati, M. (2004). An electron beam imaging system for quality assurance in IORT. Nuclear Instruments and Methods in Physics Research, Section B: Beam Interactions with Materials and Atoms, 213, 616 - 620. https://doi.org/10.1016/S0168-583X(03)01658-6