Characterisation of tissue shrinkage during microwave thermal ablation

Laura Farina, Noam Weiss, Yitzhak Nissenbaum, Marta Cavagnaro, Vanni Lopresto, Rosanna Pinto, Nevio Tosoratti, Claudio Amabile, Simone Cassarino, S. Nahum Goldberg

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Results: Overall, substantial shrinkage of 52-74% of initial tissue volume was noted. The shrinkage was non-uniform over time and space, with observed asymmetry favouring the radial (23-43 % range) over the longitudinal (21-29%) direction. Algorithmic relationships for the shrinkage as a function of time were demonstrated. Furthermore, the smallest cubes showed more substantial and faster contraction (28-40% after 1 min), with more considerable volumetric shrinkage (>10%) in muscle than in liver tissue. Additionally, CT imaging demonstrated initial expansion of the tissue volume, lasting in some cases up to 3 min during the microwave ablation procedure, prior to the contraction phenomenon.
Original languageEnglish
Pages (from-to)419 - 428
Number of pages10
JournalInternational Journal of Hyperthermia
Issue number7
Publication statusPublished - 1 Nov 2014
Externally publishedYes


All Science Journal Classification (ASJC) codes

  • Radiological and Ultrasound Technology
  • Physiology
  • Physiology (medical)
  • Cancer Research

Cite this

Farina, L., Weiss, N., Nissenbaum, Y., Cavagnaro, M., Lopresto, V., Pinto, R., Tosoratti, N., Amabile, C., Cassarino, S., & Goldberg, S. N. (2014). Characterisation of tissue shrinkage during microwave thermal ablation. International Journal of Hyperthermia, 30(7), 419 - 428.