Chemical characterization of Narcissus poeticus from sirente-velino (apennines-Italy): Galantamine accumulation and distribution of allergenic compounds in the flower

Donatella Ferri, Carla Ubaldi, Giordana Marcozzi, Paolo Fasciani, Loretta Bacchetta, Loretta Pace

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Abstract

Species of Narcissus (family Amaryllidaceae) are a potential source for large-scale extraction of alkaloids and fragrances. The bulbs typically accumulate a large number of alkaloids, including galantamine, a benzazepine alkaloid proven to be a cholinesterase inhibitor and which is used in the treatment of Alzheimer's disease. The presence of galantamine in N. poeticus L. collected in Abruzzo (Italy) was assessed and several levels of alkaloid were found in all parts of the plant (flower, stem, bulb and root) and not only in the bulb. The amount of galantamine obtained was tested by using two different extraction solvents. Extraction of N. poeticus absolute from the flowers was also performed, as this product is an important floral note in perfumery, and the distribution of allergenic compounds in the coronas and in the tepals was assessed. Moreover, the in vitro propagation of N. poeticus was tested as it may be a valuable resource from which to produce biomolecules, as an alternative to chemical synthetic processes.
Original languageEnglish
Pages (from-to)15 - 18
Number of pages4
JournalNatural Product Communications
Volume12
Issue number1
Publication statusPublished - 2017
Externally publishedYes

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All Science Journal Classification (ASJC) codes

  • Pharmacology
  • Drug Discovery
  • Plant Science
  • Complementary and alternative medicine

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