Comparison between two absolute methods used for 177Lu activity measurements and its standardization

M. Capogni, M.L. Cozzella, P. De Felice, A. Fazio

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Abstract

A177Lu primary standard was developed at the ENEA-INMRI in the frame of an international comparison organized by BIPM and piloted by NIST (USA). The CIEMAT/NIST method with3H standard source as tracer was used for standardizing a solution of177Lu. The activity value was compared also with the measurements of the same mother solution carried out by the 4πγ integral counting method. Particular efforts were made to identify and quantify the long-lived177mLu impurity in the mother solution. The results obtained by the two methods are in good agreement within their standard uncertainties. The arithmetic mean of the two values is in good agreement with the Comparison Reference Value (CRV). By the new primary standard two well-type ionization chambers (ICs), one fixed and the other one portable, were calibrated with an uncertainty lower than 2%. These ICs are used for routinely applications in the activity measurements of short-lived radionuclides particularly useful for medical applications. © 2012 Elsevier Ltd.
Original languageEnglish
Pages (from-to)2075 - 2080
Number of pages6
JournalApplied Radiation and Isotopes
Volume70
Issue number9
DOIs
Publication statusPublished - Sep 2012
Externally publishedYes

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All Science Journal Classification (ASJC) codes

  • Radiation

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