Panax ginseng C.A. Meyer roots are highly prized in international markets for their medicinal properties. The present study focussed on the enhanced production of the bioactive anti-cancer protopanaxatriol group of ginsenosides in adventitious roots of P. ginseng in bioreactor cultures by feeding the biogenetic precursor, squalene. HPLC-MS analysis of the saponin fraction indicated higher accumulation of the protopanaxatriol group of ginsenosides (Rg10.96 mg g-1, Rg20.09 mg g-1and Re 1.91 mg g-1DW) in 40 d-old squalene-fed adventitious roots compared to controls. The results allow predictions of the biosynthetic pathway from squalene to ginsenosides in adventitious roots.
|Pages (from-to)||549 - 552|
|Number of pages||4|
|Journal||Journal of Horticultural Science and Biotechnology|
|Publication status||Published - 2006|
All Science Journal Classification (ASJC) codes
Sivakumar, G., Yu, K. W., & Paek, K. Y. (2006). Enhanced production of bioactive ginsenosides from adventitious roots of Panax ginseng in bioreactor culture. Journal of Horticultural Science and Biotechnology, 81(3), 549 - 552. https://doi.org/10.1080/14620316.2006.11512102