Esposizione a fibre anfiboliche e neoplasie del tratto digerente: Indagine epidemiologica nel lagonegrese

Fabrizio Giannandrea, A. Binazzi, F. Giordano, I. Figà-Talamanca

Research output: Contribution to journalArticle

Abstract

The relation between asbestos exposure and gastrointestinal cancer (GC) continues to be controversial. Previous studies of predominantly ecological design have indicated a possible elevation of GC risk in population groups exposed to ingested asbestos fibres. In the present study the GC risk was investigated in Lagonegro district (Southern Italy) where a previous study demonstrated the presence of environmental tremolite exposure. The survey comprises the total of 427 deaths for GC in the period 1980-2001 (ENEA-Database). Standardized mortality ratios (SMR) were calculated reporting the number of the observed cases to the expected values among the inhabitants of the local sites with reference to the specific mortality rates for sex and age in Basilicata region. The SMR for the esophageal cancer had increased (133.09; 95% CI 98-175) in the whole district and particularly in the village of Cersosimo (835.48; 95% CI 277-2139). A greater risk was also observed for gastric cancer in the village of Calvera (SMR: 304.63; 95% CI 146-560), Lauria (SMR: 142.3; 95% CI 111-179) and San Costantino Albanese (SMR: 182.09; 95% CI 90-325). Oro-pharyngeal cancer mortality was relevant in the municipalities of Teana (SMR: 537.23; 95% CI 146-1375) and Castelluccio Inferiore (SMR: 268.22; 95% CI 98-583). In some of these villages (all neighbouring) pleural mesothelioma cases have been previously identified and associated to the presence of tremolite outcrops.
Original languageItalian
Pages (from-to)334 - 335
Number of pages2
JournalGiornale Italiano di Medicina del Lavoro ed Ergonomia
Volume28
Issue number3
Publication statusPublished - Jul 2006
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Public Health, Environmental and Occupational Health
  • Rehabilitation

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