Frequency spectra of induced transmembrane potential correlate with nanosecond bipolar pulse cancellation of electropermeabilization

Caterina Merla, Andrei G. Pakhomov, P. Thomas Vernier

Research output: Contribution to conferencePaper

Abstract

A simple prediction method for the bipolar pulse cancellation effect is proposed, based on analysis of single-cell transmembrane potential frequency spectra for a variety of unipolar and bipolar input signals in the nanosecond and microsecond time scales. Our evaluations are in good agreement with experimental results for electropermeabilization-induced Ca2+influx using 300 ns, 750 kV/m pulses.
Original languageEnglish
DOIs
Publication statusPublished - 14 Jul 2017
Externally publishedYes
Event14th International Conference on Synthesis, Modeling, Analysis and Simulation Methods and Applications to Circuit Design, SMACD 2017 - Giardini Naxos, Taormina, Italy
Duration: 14 Jul 2017 → …

Conference

Conference14th International Conference on Synthesis, Modeling, Analysis and Simulation Methods and Applications to Circuit Design, SMACD 2017
CountryItaly
CityGiardini Naxos, Taormina
Period14/7/17 → …

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All Science Journal Classification (ASJC) codes

  • Hardware and Architecture
  • Electrical and Electronic Engineering
  • Modelling and Simulation

Cite this

Merla, C., Pakhomov, A. G., & Vernier, P. T. (2017). Frequency spectra of induced transmembrane potential correlate with nanosecond bipolar pulse cancellation of electropermeabilization. Paper presented at 14th International Conference on Synthesis, Modeling, Analysis and Simulation Methods and Applications to Circuit Design, SMACD 2017, Giardini Naxos, Taormina, Italy. https://doi.org/10.1109/SMACD.2017.7981604