Highly miniaturized system for on-chip detection of DNA

D. Caputo, F. Costantini, N. Lovecchio, V. Viri, M. Tucci, P. Mangiapane, A. Ruggi, G. Petrucci, A. Nascetti, G. De Cesare

Research output: Contribution to conferencePaper

1 Citation (Scopus)

Abstract

This paper reports on the development of a lab-on-chip system for detection of DNA through the [Ru(phen)2(dppz)]2+fluorescent intercalating dye. The device includes on the same glass substrate amorphous silicon photosensors, a thin film interferential filter and a microfluidic network based on polydimethylsiloxane. The suitability of the miniaturized system in detecting the fluorescence variation of the ruthenium complex, working as DNA intercalating molecules, is demonstrated.
Original languageEnglish
Publication statusPublished - 2016
Externally publishedYes
Event20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016 - Dublin, Ireland
Duration: 1 Jan 2016 → …

Conference

Conference20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016
CountryIreland
CityDublin
Period1/1/16 → …

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All Science Journal Classification (ASJC) codes

  • Control and Systems Engineering

Cite this

Caputo, D., Costantini, F., Lovecchio, N., Viri, V., Tucci, M., Mangiapane, P., ... De Cesare, G. (2016). Highly miniaturized system for on-chip detection of DNA. Paper presented at 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016, Dublin, Ireland.