Medical diagnostics by laser-based analysis of exhaled breath

G. Giubileo

Research output: Contribution to conferencePaper

21 Citations (Scopus)


Many trace gases can be found in the exhaled breath, some of them giving the possibility of a non invasive diagnosis of related diseases or allowing the monitoring of the disease in the course of its therapy. In the present lecture the principle of medical diagnosis based on the breath analysis will be introduced and the detection of trace gases in exhaled breath by high-resolution molecular spectroscopy in the IR spectral region will be discussed. A number of substances and the optical systems for their laser detection will be reported. The following laser based experimental systems has been realised in the Molecular Spectroscopy Laboratory of ENEA in Frascati for the analysis of specific substances in the exhaled breath. A tuneable diode laser absorption spectroscopy (TDLAS) apparatus for the measurement of13C/12C isotopic ratio in carbon dioxide, a TDLAS apparatus for the detection of CH4, and a CO2laser based photoacoustic system to detect trace ethylene at atmospheric pressure. The experimental set-up for each one of the a.m. optical systems will be shown and the related medical applications will be illustrated. The concluding remarks will be focused on chemical species that are of major interesting for medical people today and their diagnostic utility.
Original languageEnglish
Publication statusPublished - 2002
Externally publishedYes
EventALT '01 International Conference on 'Advanced Laser Technologies - , Romania
Duration: 1 Jan 2002 → …


ConferenceALT '01 International Conference on 'Advanced Laser Technologies
Period1/1/02 → …


All Science Journal Classification (ASJC) codes

  • Electrical and Electronic Engineering
  • Condensed Matter Physics

Cite this

Giubileo, G. (2002). Medical diagnostics by laser-based analysis of exhaled breath. Paper presented at ALT '01 International Conference on 'Advanced Laser Technologies, Romania.