In this article, a three-dimensional inversion recovery sequence was optimized with the aim of generating in vivo volume T1maps of the heart using a 1.5-T MR system. Acquisitions were performed before and after gadolinium diethylenetriamine penta-acetic acid (Gd-DTPA) administration in one patient with hypertrophic cardiomyopathy and in two healthy volunteers. Data were acquired with a multishot fast field echo readout using both ECG and respiratory triggers. A dedicated phantom, composed of four solutions with different T1values, was positioned on the subjects' thoracic region to perform patient-specific calibration. Pixel based T1maps were calculated with a custom Matlab®code. Phantom measurements showed a good accuracy of the technique and in vivo T1estimation of liver, skeletal muscle, myocardium, and blood resulted in good agreement with values reported in the literature. Multiple three-dimensional inversion recovery technique is a feasible and accurate method to perform T1volume mapping. Magn Reson Med, 2013. © 2012 Wiley Periodicals, Inc. Copyright © 2012 Wiley Periodicals, Inc.
All Science Journal Classification (ASJC) codes
- Radiology Nuclear Medicine and imaging
Coniglio, A., Di Renzi, P., Vilches Freixas, G., Della Longa, G., Santarelli, A., Capparella, R., ... Begnozzi, L. (2013). Multiple 3D inversion recovery imaging for volume T. Magnetic Resonance in Medicine, 69(1), 163 - 170. https://doi.org/10.1002/mrm.24248