One-inch field of view imaging probe for breast cancer sentinel node location

Giovanni D'Errico, Raffaele Scafé, Alessandro Soluri, Alfiero Schiaratura, Anna Maria Mangano, Vincenzo David, Francesco Scopinaro

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6 Citations (Scopus)


The already reported 1-in.2field of view mini gamma camera known since 1998 with the name of Imaging Probe (IP), has been used for sentinel node localization by a medical equipe that, though trained by the group of nuclear physicians of the University "La Sapienza" who first conceived and used this detector, has used IP in its own Hospital to: (1) gain experience for future use during operations - a cooperative work on IP radio guided orthopaedic operations has already started working, and (2) to start with IP multicenter trials. In six patients with breast cancer, who underwent lymphoscintigraphy for sentinel node biopsy, sentinel node was checked and located with IP and non-imaging Neoprobe 2000 CdTe (Zn) probe, independent of location by means of large field of view Anger camera. Operators who used Neoprobe and IP were blinded to each other and not aware of the results of Anger camera imaging. Anger camera, as well as IP and neoprobe detected 7 nodes in 6pts. Detection time was 2′, 06″ SD 26″ with IP and 2′, 18″ SD 47″ with neoprobe 2000. The most difficult to find node required 2min and 56s - inside sd - for IP detection and 3min and 45s with neoprobe. Subjective impression of being sure of having detected sentinel node was: absolutely sure on 7/7 nodes with IP and on 5/7 nodes with neoprobe. © 2002 Elsevier Science B.V. All rights reserved.
Original languageEnglish
Pages (from-to)105 - 109
Number of pages5
JournalNuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment
Issue number1
Publication statusPublished - 21 Jan 2003
Externally publishedYes


All Science Journal Classification (ASJC) codes

  • Nuclear and High Energy Physics
  • Instrumentation

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