Preparation of "high specific activity" radiochemical forms of vanadium, manganese and thallium for metallo-toxicological studies

Mauro Bonardi, Claudio Birattari, Flavia Groppi, Luigi Gini, Alberto Ghioni, Hae Song Mainardi, Dolores Arginelli, Mario Gallorini, Enrico Rizzio, Enrico Sabbioni

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Abstract

In this paper are presented the production methods for very "high specific activity" radionuclides (HSA-RN) of vanadium, manganese and thallium which have been developed in our laboratories for labelling different chemical forms of these elements present in the echo-systems in ultra-trace amounts, for metallo-toxicological and bio-kinetic studies. Use was made of both cyclotron and thermal nuclear reactor. If the nuclear reaction product has atomic number different from irradiated target, it is possible separating the radioactive nuclide from irradiated target, without addition of isotopic carrier. This kind of radionuclide is named No Carrier Added, NCA, and his specific activity, AS is very high and can reach values close to the theoretical Carrier Free one, CF. The experimental determination of specific activity, chemical and radiochemical purities is mandatory for all these kinds of applications.
Original languageEnglish
Pages (from-to)363 - 372
Number of pages10
JournalAnnali di Chimica
Volume93
Issue number4
Publication statusPublished - Apr 2003
Externally publishedYes

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All Science Journal Classification (ASJC) codes

  • Analytical Chemistry
  • Environmental Science(all)

Cite this

Bonardi, M., Birattari, C., Groppi, F., Gini, L., Ghioni, A., Mainardi, H. S., ... Sabbioni, E. (2003). Preparation of "high specific activity" radiochemical forms of vanadium, manganese and thallium for metallo-toxicological studies. Annali di Chimica, 93(4), 363 - 372.