Separation of carrier-free

L. Pietrelli, L.F. Mausner, K.L. Kolsky

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Abstract

The radiochemical separation of no-carrier-added (NCA)47Sc fromnatTi targets has been studied. Scandium-47, a medium-energy β-emitter, is intended for use with labelled tumor associated monoclonal antibodies for radiotherapy. Several radiochemical methods for the separation of NCA47Sc from macroquantities of titanium and other impurities were tested. Four different procedures based on ion exchange, solvent extraction and extraction chromatography are reported. For each method, parameters such as the distribution coefficient, kinetics and recoveries are reported. The selective separation can be performed rapidly by all methods. © 1992 Akadémiai Kiadó.
Original languageEnglish
Pages (from-to)335 - 345
Number of pages11
JournalJournal of Radioanalytical Chemistry
Volume157
Issue number2
DOIs
Publication statusPublished - Mar 1992
Externally publishedYes

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All Science Journal Classification (ASJC) codes

  • Analytical Chemistry
  • Nuclear Energy and Engineering
  • Radiology Nuclear Medicine and imaging
  • Pollution
  • Spectroscopy
  • Public Health, Environmental and Occupational Health
  • Health, Toxicology and Mutagenesis

Cite this

Pietrelli, L., Mausner, L. F., & Kolsky, K. L. (1992). Separation of carrier-free. Journal of Radioanalytical Chemistry, 157(2), 335 - 345. https://doi.org/10.1007/BF02047448